Preheat the oven to 350°F (175°C) and line a baking sheet with parchment paper.
In a large mixing bowl, combine the red velvet cake mix, eggs, and vegetable oil until thoroughly blended.
Fold in the white chocolate chips and softened cream cheese until evenly distributed.
Scoop tablespoons of the dough onto the prepared baking sheet, spacing them about 2 inches apart.
Bake in the preheated oven for 10-12 minutes, or until the edges are set but the centers are still soft.
Remove from the oven and let the cookies cool on the baking sheet for 5 minutes before transferring to a wire rack.
Once cooled, dust with powdered sugar, if desired, before serving.